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Patient data recorded over time form unique patient histories that can predict future disease progression and thereby facilitate effective care. However, digital medicine often uses limited health events data from a single or small number of time points, ignoring additional information encoded in patient trajectories. This paper provides an overview of recent efforts to develop AI solutions that incorporate trajectories, with a particular focus on the implications for developing disease models from patient trajectories in the context of the typical AI workflow, and concludes with a discussion of how such AI solutions will enable the development of robust models for personalized risk assessment, subtyping, and disease pathway discovery.
See Allam et al., JMIR